FDA Panel Votes Down Libido-Boosting Drug for Women
6/19/2010 ...
An FDA advisory committee has decided that the makers of the investigational drug flibanserin (Girosa) -- often dubbed the female Viagra -- haven’t proved that the pill treats hypoactive sexual-desire disorder (HSDD).
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Abstract: Aromatase Inhibitors to Augment Height: Continued Caution and Study Required
4/8/2009 ...
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FDA Suspends Rotarix vaccine
3/22/2010 ...
The FDA is temporarily suspending use of Rotarix rotavirus vaccine due to viral contamination of the vaccine.
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Omega-3 Fatty Acid Protects Against Polyps (CME/CE)
3/23/2010 ...
An omega-3 polyunsaturated fatty acid significantly reduced both the number and size of rectal polyps in patients with familial adenomatous polyposis
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Cryotherapy Conserves the Breast
3/18/2010 ...
Multiprobe cryotherapy was safe and effective in breast cancer patients and didn’t require subsequent surgery to ensure that all tumor cells were killed
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Testosterone Gel Improves Diabetes in Hypogonadal Men (CME/CE)
3/17/2010 ...
Topical testosterone replacement reduced insulin resistance and glycated hemoglobin in men who were deficient in the hormone and at risk for, or diagnosed with type 2 diabetes
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AAPM: Online Program Helps Manage Pain (CME/CE)
2/10/2010 ...
SAN ANTONIO -- A personalized, online self-management program helped patients with pain syndromes improve coping skills and reduce stress and depression
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SSRI and Tamoxifen Increase Mortality Risk (CME/CE)
2/9/2010 ...
Overlapping use of tamoxifen and the antidepressant paroxetine (Paxil) significantly increases the risk of breast cancer mortality
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'Artificial Pancreas' Improves Glucose Control at Night (CME/CE)
2/6/2010 ...
Closed-loop insulin delivery systems can improve overnight blood sugar control and reduce hypoglycemia risk in young patients with type 1 diabetes
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Lancet Retracts 1998 MMR-Autism Paper
2/3/2010 ...
Editors of The Lancet have retracted the 1998 study that first suggested autism might be caused by the MMR vaccine
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FDA Approves New Lead for Chronic Pain
12/7/2009 ...
The FDA has approved a new surgical lead for chronic pain management in neurostimulation therapy.
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12/04 Exposure to Lead Linked with Psychological Problems (CME/CE)
12/4/2009 ...
Greater environmental lead exposure in adults -- even at levels generally considered to pose little or no risk -- was associated with an increased likelihood of depression and panic disorder
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Oxygen Does Ease Pain of Cluster Headache (CME/CE)
12/8/2009 ...
The benefits of inhaled oxygen for acute cluster headache attacks have been confirmed in a randomized, controlled trial.
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High-dose Folic Acid and B12 May Hike Cancer Risk
11/18/2009 ...
High-dose folic acid and vitamin B12 supplements were associated with an increased incidence of cancer — particularly lung cancer
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AHA: FDA Drops Clopidogrel Bomb at AHA
11/17/2009 ...
The FDA has issued a public health advisory warning patients and physicians that concomitant use of clopidogrel (Plavix) and omeprazole (Prilosec and Prilosec OTC) blunts the antiplatelet effect of clopidogrel
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New Antipsychotics Lead to Weight Gain in Young Patients (CME/CE)
10/28/2009 ...
Oct 27 - In children and adolescents, the so-called atypical antipsychotic agents lead to a marked and rapid weight gain, researchers said.
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More Evidence for Link Between Stroke and Migraine (CME/CE)
10/28/2009 ...
Oct 27 - Migraine sufferers might have an increased risk of ischemic stroke, especially if the headache is accompanied by an aura, a meta-analysis showed.
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Kids' Hypertension Linked to Faster Bone Growth (CME/CE)
10/19/2009 ...
Oct 19 - Hypertension in childhood may be a sign of abnormal growth and accelerated maturation in other body systems as well, researchers said.
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Thyroidectomy Safe in the Elderly (CME/CE)
10/19/2009 ...
Oct 19 2009 - Thyroid surgery is no more risky in elderly patients than in the young, a prospective study found.
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Drop in Oxygen Saturation in Apnea Tied to Obesity (CME/CE)
10/7/2009 ...
Oct 7 - Obese patients may experience more severe blood oxygen desaturation during apnea and hypopnea events, researchers say.
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Shingles Raises Risk of Stroke (CME/CE)
10/7/2009 ...
Oct 7 2009 - Adults who had had herpes zoster were 31% more likely to suffer a stroke within a year than were people who had not had shingles, Taiwanese researchers reported online in Stroke.
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ASCO Breast: Most Deaths Fall Outside Screening Programs (CME/CE)
10/7/2009 ...
Oct 7 - Nearly three-quarters of breast cancer deaths occur among women who don't get regular screening mammograms, according to a large population-based study.
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Tamoxifen May Increase Risk of Some Forms of Breast Cancer (CME/CE)
8/26/2009 ...
Aug 25 - Breast cancer survivors who take tamoxifen for secondary prevention may actually increase their risk of the more difficult to treat estrogen receptor-negative cancers, according to a population-based study.
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Testosterone Supplementation Benefits HF in Older Men (CME/CE)
8/25/2009 ...
Testosterone injections significantly improved the strength, endurance, and physical function of elderly men with heart failure, a double-blind Italian study found.
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High Diastolic BP Linked to Cognitive Problems (CME/CE)
8/25/2009 ...
Aug 25 - Elevated diastolic blood pressure appears to be associated with cognitive impairment in people 45 and older, a cross-sectional study showed.
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Sexual Abuse Linked to Somatic Disorders
8/20/2009 ...
Aug 20 - Sexual abuse is associated with an increased risk of somatic disorders, in which patients report physical symptoms or complaints with no clear underlying cause, a review of nearly two dozen studies concluded.
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FDA Cracks Down on Ibuprofen Skin Creams
8/21/2009 ...
Aug 21 - The FDA has issued warning letters to eight companies demanding that they stop marketing unapproved topical products containing ibuprofen as over-the-counter pain relievers.
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Online Therapy Successful for Depression
8/21/2009 ...
Aug 21 - Online cognitive behavioral therapy (CBT) for depression -- with patients and therapists communicating in real time via instant messaging -- was effective in a randomized trial and could broaden access to treatment, a study found.
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Tailor Treatment of Depression in Pregnancy
8/21/2009 ...
Aug 21 - A pregnant woman's depression and the drugs used to treat it can both affect the health of her newborn, so physicians should tailor their treatment carefully and take the mother's wishes into account
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FDA: Some Diabetes Monitoring Strips Confused by Nonglucose Sugars
8/17/2009 ...
Aug. 17 -- The FDA warned against the use of GDH-PQQ glucose test strips by patients in therapies that include certain nonglucose sugars because of a risk of false results that might prompt a dangerous, or even lethal overdose of insulin.
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FDA Warns of Pediatric Cancer Risk with TNF Blockers
8/4/2009 ...
Aug 4 2009 -- The FDA called for stronger warnings in prescribing information for tumor necrosis factor (TNF) blockers to highlight a greater risk of cancer in children and adolescents.
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Alzheimer's Linked to Cholesterol Level in Middle Age
8/4/2009 ...
Aug 4 - Even modestly elevated cholesterol in midlife portends greater Alzheimer's disease risk in old age, researchers found.
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FDA Okays First Monthly Antipsychotic Drug
8/5/2009 ...
Aug 5 -- The FDA has approved the injectable maintenance drug paliperidone palmitate (Invega Sustenna), making it the first once-monthly, atypical antipsychotic for schizophrenia.
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Risk of Diabetes Linked to Sex Hormone Protein
8/6/2009 ...
Aug 6 - People with low blood levels of a protein that regulates sex hormones are at higher risk of diabetes, and genetics may play a role in determining both the levels and the risk
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FDA Urges Screening for Melamine in Drug Production
8/7/2009 ...
Aug 07 -- The FDA has called for routine testing for melamine contamination in certain ingredients used in the manufacture and preparation of drugs.
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Urinary Marker Predicts Complications in Type 1 Diabetes
8/7/2009 ...
Aug 07 - Increased urinary excretion of the protein IgM in patients with type 1 diabetes was associated with an elevated risk for cardiovascular mortality and end-stage renal disease and may represent a prognostic marker for these complications
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Urine Test May Predict Drug Responses
8/10/2009 ...
Aug. 10 - A simple urine sample can be used to tell how people will respond to the common analgesic acetaminophen, researchers said
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Sleep, Behavior Improvements After Tonsil Removal Called Durable
7/20/2009 ...
July 20 -- Children who had tonsils and adenoids removed to correct abnormal breathing during sleep still showed substantial improvements from baseline after 2.5 years, researchers said.
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FDA Approves Seasonal Flu Vaccine
7/20/2009 ...
July 20 -- The FDA has approved a vaccine for the 2009-2010 flu season that protects against a trio of expected influenza strains, but the vaccine will not protect against the 2009 H1N1 pandemic flu virus.
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ICAD: Fish Oil Fails to Slow Alzheimer's Decline
7/13/2009 ...
July 13 -- Supplements of docosahexaenoic acid (DHA), the omega-3 fatty acid found in fish oil, failed to slow the progression of Alzheimer's disease in a 402-patient clinical trial, researchers reported.
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Angina Frequency Linked to Depression, Anxiety
6/29/2009 ...
June 29 -- Ischemic heart patients with depression and anxiety were more likely to suffer chest pain than patients without those psychosocial symptoms, a new study shows.
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Mixed Message on Insulin Glargine Cancer Risk
6/29/2009 ...
June 29 -- Studies examining a possible cancer link to insulin glargine (Lantus) produced mixed conclusions that drew quick, reassuring responses from diabetes authorities.
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Patients Not Always Given Important Test Results
6/22/2009 ...
June 22 -- Abnormal test results are not communicated to patients more than 6% of the time, researchers in a multicenter study found.
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Obesity Surgery Reduces Cancer Risk in Women
6/23/2009 ...
June 23 -- Obese women had a 42% reduction in cancer risk following bariatric surgery, data from a Swedish study showed.
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Later-Life Brain Lesions Found in Migraine-Prone Women
6/23/2009 ...
June 23 -- Middle-aged women who suffered migraine headaches accompanied by sensory disturbances or difficulty speaking (aura) had higher incidence of brain lesions later in life, according to a study of Icelandic patients.
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ENDO: Testosterone May Have Heart Benefits in Male Metabolic Syndrome
6/17/2009 ...
6/17/2009 Older hypogonadal men with metabolic syndrome had substantial improvement in cardiovascular risk factors with testosterone replacement therapy, according to two studies reported here.
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APSS: Sleep Apnea Not Limited to Obese Patients
6/17/2009 ...
June 17 -- Obstructive sleep apnea was the culprit in half of patients with relatively normal weight who complained of daytime sleepiness, researchers said here.
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ENDO: Pituitary Workup Warranted after Head Trauma
6/17/2009 ...
June 17 -- Moderate to severe brain trauma increases the risk of pituitary abnormalities that warrant investigation before they become symptomatic, according to investigators in an ongoing study.
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Low Vitamin D May Slow Cognition in Older Men
5/22/2009 ...
May 21 - Here's yet another reason to worry about vitamin D deficiency: low levels of 25-hydroxyvitamin D may be linked to slower information processing in men of middle age and older, researchers say.
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Pregnancy Makes Thyroid Surgery Riskier
5/18/2009 ...
May 18 - Pregnancy increases the risk of poor clinical outcomes and higher costs after surgery, according to a study of 31,000 women who had thyroid or parathyroid procedures.
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FDA Investigates Heparin Link in Two Delaware Deaths
5/13/2009 ...
May 12 - The FDA is investigating a possible link to heparin in the deaths of two Delaware residents who suffered cerebral hemorrhages following heparin treatment.
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AUA: PSA at Age 60 Predicts Prostate Cancer Mortality by 85
4/27/2009 ...
April 27 -- A man's PSA value at age 60 reliably predicted the risk of fatal prostate cancer over the next 25 years, according to data from a Swedish study.
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Pituitary insufficiency after traumatic brain injury
2/2/2009 ...
Neuropsychological complaints after TBI are more frequent than PI. Brain tissue damage is most important than PI in the development of psychological changes after TBI.
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Pituitary insufficiency after traumatic brain injury - Clinical Study
2/2/2009 ...
Wachter D et al. - Neuropsychological complaints were present in 67% of the patients and were associated with intracerebral hemorrhagic lesions and not PI.
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Gamma knife stereotactic radiosurgery of Nelson syndrome
11/12/2008 ...
European Journal of Endocrinology 11/12/2008
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FDA Reports Nationwide Recall of Mislabeled ReliOn Insulin Syringes
11/5/2008 ...
The U.S. Food and Drug Administration is notifying health care professionals and patients that Tyco Healthcare Group LP (Covidien) is recalling one lot of ReliOn sterile, single-use, disposable, hypodermic syringes with permanently affixed hypodermic needles
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FDA Reports Nationwide Recall of Mislabeled ReliOn Insulin Syringes
The U.S. Food and Drug Administration is notifying health care professionals and patients ...
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NIH to Set Brain Tumor Research Priorities
In Current Edition Of Viewpoint From Veritas Medicine
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Cushing's Disease One of the Hardest to Diagnose
Doctors rarely see condition and end up treating secondary disease instead of cause
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European Journal of Neuro-Endocrinology, Jan 2006 - THE COST OF MEDICAL CARE FOR THE ACROMEGALIC PATIENT
by Robert Knutzen, CEO PNA and Shereen Ezzat, M.D.
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TESTOSTERONE THERAPY FOR ANDROGEN DEFICIENT MEN - New Clinical Guideline from the Endocrine Society
by Cathy Kristiansen, Editor
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TOUCH BRIEFINGS: US ENDOCRINE DISEASE
Recent articles published by Touch Briefings:
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U.S. Food and Drug Administration Enforcement Report
Recalls and Field Corrections: Drugs -- Class III
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King Pharmaceuticals, announcement of discontinuance of the manufacture of FLORINEF Acetate (Fludrocortisone Acetate Tablets, USP)
Decision based upon many factors, including understanding of current medical therapy and general availability of generic alternatives.
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FDA Reports Nationwide Recall of Mislabeled ReliOn Insulin Syringes
The U.S. Food and Drug Administration is notifying health care professionals and patients that Tyco Healthcare Group LP (Covidien) is recalling one lot of ReliOn syringes
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Important: Keep the FDA Informed!
If you are having trouble with ANY of your medications:
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MicroRNAs and Possible Role in Pituitary Adenoma
10/27/2008 ...
Zatelli MC et al. - This review reports the current knowledge of microRNA (miRNA) expression in pituitary adenomas
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Behavioral neuroendocrinology and treatment of anorexia nervosa
10/23/2008 ...
Sodersten P et al. - Outcome in anorexia nervosa remains poor and a new way of looking at this condition is therefore needed
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Hypothyroidism in Male Patients
10/23/2008 ...
A Descriptive, Observational and Cross-Sectional Study in a Series of 260 Men
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Thyroid Function After Unilateral Total Lobectomy
10/21/2008 ...
Carlucci DD et al. - Postoperative hypothyroidism appeared in 32.8% of the cases in this series
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Effect of Statins on PSA May Confound Biopsy Decision
10/28/2008 ...
DURHAM, N.C. -- Statin therapy lowers prostate-specific antigen levels
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Antipsychotics for acute and chronic pain in adults
10/30/2008 ...
Seidel S et al. - Antipsychotics might be used as an add-on therapy in the treatment of painful conditions.
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Childbirth and HRT May Boost Need for Joint Replacement
10/31/2008 ...
OXFORD, England -- Increasing parity for women who later take postmenopausal hormone replacement therapy appears to have a higher incremental risk of severe hip and knee osteoarthritis
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Acromegaly secondary to an incidentally discovered tumour
11/3/2008 ...
Growth-hormone-releasing hormone secreting bronchial carcinoid tumour associated to a pituitary incidentaloma
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Vitamin K supplementation in postmenopausal women with osteopenia (ECKO trial): A randomized controlled trial
11/7/2008 ...
Cheung AM et al. - Daily 5 mg dose of vitamin K1 supplementation for 2 to 4 y does not protect against age-related decline in BMD
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Diagnosis of secondary adrenal insufficiency in patients with hypothalamic-pituitary disease
10/29/2008 ...
Comparison between serum and salivary cortisol during the high-dose short synacthen test
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Clinical Use of Cabergoline as Primary and Adjunctive Treatment for Acromegaly
10/29/2008 ...
Moyes V et al. - Cabergoline can be an effective and well tolerated primary or adjunctive therapy for acromegaly
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Male Sex Hormones May Influence the Symptoms of Irritable Bowel Syndrome in Young Men
11/3/2008 ...
Kim BJ et al. - Sex hormone status in young men differ from those in older men and may play an important role in the pathophysiology of IBS
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Neoadjuvant and adjuvant hormone therapy: how and when
10/30/2008 ...
Poppel HV - In a review to discuss whether hormone therapy (HT) in either a neoadjuvant or adjuvant setting can offer a survival benefit for pts with prostate cancer (PCa)
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Lipid lowering in diabetes mellitus
11/7/2008 ...
Betteridge DJ et al. – This review article reports that benefits of statin therapy in diabetes are confirmed and extended
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Cardiovascular Outcomes in Trials of Oral Diabetes Medications
10/28/2008 ...
Selvin E et al. - Meta-analysis suggested that, compared with other oral diabetes agents and placebo, metformin was moderately protective and rosiglitazone possibly harmful
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Management of Graves hyperthyroidism in pregnancy
11/4/2008 ...
Focus on both maternal and foetal thyroid function, and caution against surgical thyroidectomy in pregnancy.
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Erectile dysfunction as a coronary artery disease risk equivalent
Lee JH et al. – Erectile dysfunction is significantly associated with abnormal coronary artery calcification
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Undescended testes: A consensus on management
11/4/2008 ...
Ritzen M et al. - The unanimous conclusion of the group was that surgery is generally the preferred mode of treatment, rather than hCG or GnRH.
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Safety of statins
Brown WV et al. – A review summarizes evidence for reported adverse effects during statin use in hypercholesterolemia
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GnRH analogues: Applications in assisted reproductive techniques
10/10/2008 ...
This shift in practice is occurring alongside gathering momentum in favour of milder stimulation protocols and a new perception of what constitutes successful treatment.
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Hormone replacement therapy post Women's Health Initiative study: where do we stand
11/10/2008 ...
Calleja-Agius J et al. - There is a definite decline in the use of hormone replacement therapy among menopausal women.
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Depression and Bone Metabolism
Williams LJ et al. - The possible association between psychiatric illness, in particular depression, and osteoporosis has been the subject of a growing body of research
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Lithium Treatment and Risk of Dementia
Kessing LV et al. - Continued lithium treatment was associated with reduction of the rate of dementia
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Pituitary-adrenal function in patients with acute subarachnoid hemorrhage
10/13/2008 ...
Bendel S et al. - Calculation of serum free cortisol concentration was not helpful in identifying patients with potential hypocortisolism.
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Retesting the childhood-onset GH deficient patient
11/4/2008 ...
GH deficiency (GHD) in adults has to be shown by a single provocative test, provided that it is validated.
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A single test procedure to diagnose gestational diabetes mellitus
10/2/2008 ...
Universal screening for gestational diabetes mellitus (GDM), detects more cases and improves maternal and offspring prognosis.
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Diagnosis of Growth Hormone Deficiency in Adults
Provocative Testing with GHRP6
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Clinical impact of two different intraoperative parathyroid hormone assays
11/12/2008 ...
Intraoperative parathyroid hormone (PTH) monitoring predicts successful surgery for primary hyperparathyroidism (pHPT).
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FDA Review Finds Minimal Heart Risk with Osteoporosis Drugs
11/13/2008 ...
ROCKVILLE, Md. -- The FDA’s promised analysis of atrial fibrillation events associated with bisphosphonate drugs for osteoporosis has found that the risk is minimal.
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FDA Report Questions Osteoporosis Drug
9/10/2008 ...
FDA Report Questions Osteoporosis Drug
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Review Indicates Number of Endocrinology Disease Studies Increasing
Review Indicates Number of Endocrinology Disease Studies Increasing
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Research Suggests Hormone Therapy May Lead to More Deadly Prostate Cancer
Research Suggests Hormone Therapy May Lead to More Deadly Prostate Cancer
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NIH Family Hormonal Health Symposium - 2004
NIH Family Hormonal Health Symposium - 2004
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Abstract: Medical therapy of pituitary adenomas: Effects on tumor shrinkage
9/13/2008 ...
The efficacy of dopamine-agonists (DA) in patients with prolactinomas and that of somatostatin analogues (SSA) in those with GH- and TSH-secreting adenomas is well established
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Practical Pituitary Pathology
Practical Pituitary Pathology
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MDLinx: ENDOCRINOLOGY - LIPIDS 10/08
MDLinx: ENDOCRINOLOGY - LIPIDS 10/08
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MDLinx: NEURORADIOLOGY 10/08
10/8/2008 ...
MDLinx: NEURORADIOLOGY 10/08
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MDLinx: ENDOCRINOLOGY 10/08
10/17/2008 ...
MDLinx: ENDOCRINOLOGY 10/08
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MDLinx: NEUROENDOCRINOLOGY 10/08
10/27/2008 ...
MDLinx: NEUROENDOCRINOLOGY 10/08
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Pituitary Growth Hormone Advance
Sensus Corporation’s Growth Hormone Antagonists
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Patient Survey - Possible link in avascular necrosis surgery and unrecongnized Cushing's Disease or Syndrome.
2/5/2009 ...
It may be that patients who undergo hip surgery for avascular necrosis may have unrecognized Cushing's Disease or Cushing's Syndrome.
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Management of osteoporosis in children
10/24/2008 ...
Shaw N - Osteoporosis is being increasingly recognised in pediatric practice as a consequence of several factors.
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ACR: Biologic Therapy May Be Better for Bones than Bisphosphonate
10/29/2008 ...
SAN FRANCISCO -- Women with a low bone mass may get a better treatment response with denosumab
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Teamwork Delivers Savings When Treating Chronic Conditions
8/7/2009 ...
Aug 7 - When physicians team with a nurse to deliver "proactive, evidence-based, comprehensive healthcare" to patients with chronic conditions, the benefit shows up in the bottom line, according to a new report.
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Popular Flu Drugs Have Modest Effect
8/10/2009 ...
Aug 7 - In healthy adults with seasonal flu, the antiviral drugs oseltamivir (Tamiflu) and zanamivir (Relenza) reduce the duration of symptoms by just half a day
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Drug Giant Uses Cells to Make H1N1 Vaccine
6/12/2009 ...
June 12 -- The Swiss drug giant Novartis AG says it has already produced an initial 10-liter batch of vaccine against the H1N1 pandemic influenza strain.
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Male Enhancement Supplement Recalled for Undeclared Drug
A product marketed as an herbal supplement to enhance male sexual performance has been recalled following FDA testing that revealed the presence of undeclared benzamidenafil, a phosphodiesterase-5 (PDE5) inhibitor
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FDA Yanks More Diet Pills for Undeclared Drugs
The FDA has expanded its recall of weight-loss products that contain undeclared, active ingredients including antidepressants and diuretics.
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FDA Issues Alert on Sharing of Insulin Pens
Insulin pens and insulin cartridges should not be shared between patients even if needles are switched out, the FDA has warned.
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Dizziness Linked to Bone Health
Low bone mineral density may increase the risk of benign positional vertigo, researchers found.
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ACS: New Yogurt Fights Off H. Pylori Infection
A new yogurt infused with urease antibodies may prevent gastritis and stomach ulcers by thwarting H. pylori infection, researchers here said.
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FDA Okays Treatment-Resistant Depression Indication for Combo Pill
A new indication for treatment-resistant depression in adults has been added to the olanzapine/fluoxetine combination pill (Symbyax), the drugmaker Eli Lilly announced.
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Pituitary apoplexy: correlation between magnetic resonance imaging and histopathological results.
5/10/2008 ...
The aim of this study was to correlate the magnetic resonance (MR) imaging findings in pituitary apoplexy with histopathological results and determine whether the histopathology influences clinical presentation and outcome.
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Effect of treatment with depot somatostatin analogue octreotide on (PHP) in (MEN1) patients
5/14/2008 ...
Faggiano A et al. - Six months of OCT-LAR therapy controlled hypercalcaemia and hypercalciuria in two-thirds of patients with MEN1-related PHP
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The appearance of the adrenal glands on CT in multiple endocrine neoplasia type 1
9/30/2008 ...
In patients with MEN1, adrenal limb hyperplasia and adrenal nodules are significantly more common than in the normal population
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